基因靶向技术(gene targeting)的国际研究

基因靶向技术(gene targeting)的国际研究 1985 - 2010年
已有 673 次阅读 2010-4-8 13:59 |个人分类:热点前沿|系统分类:论文交流|关键词:基因靶向技术



主题词:
基因打靶
英文名称:
Gene Targeting
树状结构号:
E05.393.335
历史注释:
95
主题词详解:
The integration of exogenous DNA into the genome of an organism at sites where its expression can be suitably controlled. This integration occurs as a result of homologous recombination.

树形结构1
研究技术
遗传学技术
基因打靶





http://www.51wendang.com/web/gopubmed/4?WEB01nvefjsp87l0mI4I1I00f01000j10040001&rl

Gene Targeting "Gene Targeting"[mesh]

10,088 of 33,384 documents semantically analyzed

Term: Gene Targeting
Description: The integration of exogenous DNA into the genome of an organism at sites where its expression can be suitably controlled. This integration occurs as a result of homologous recombination.
Synonyms: Gene Targetings

1 2
Top Years Publications
?2004 805
?2001 777
?2002 773
?2006 771
?2003 747
?2005 718
?2007 711
?2008 679
?2000 667
?1999 602
?1998 542
?2009 526
?1997 502
?1996 404
?1995 331
?1994 181
?2010 128
?1993 94
?1992 49
?1991 42
1 2

1 2 3
Top Countries Publications
?USA 4,736
?Japan 1,109
?Germany 790
?United Kingdom 652
?Canada 380
?France 353
?China 283
?Australia 212
?Netherlands 204
?Switzerland 167
?Italy 132
?Sweden 110
?South Korea 76
?Spain 75
?Belgium 70
?Austria 64
?Israel 47
?Taiwan 41
?Denmark 40
?Finland 38
1 2 3

1 2 3 ...35
Top Cities Publications
?Boston 332
?New York 309
?Houston 252
?Tokyo 244
?Bethesda 216
?London 188
?Philadelphia 153
?Toronto 151
?San Francisco 131
?Baltimore 131
?Cambridge, USA 127
?Paris 118
?St. Louis 114
?Seattle 112
?Chapel Hill 108
?San Diego 107
?Cincinnati 105
?Cambridge 102
?Kyoto 98
?Los Angeles 98
1 2 3 ...35

1 2 3 ...70
Top Journals Publications
?P Natl Acad Sci Usa 435
?Mol Cell Biol 425
?Science 247
?Gene Ther 222
?Nature 220
?J Biol Chem 201
?Nucleic Acids Res 179
?Development 163
?J Immunol 158
?J Neurosci 146
?Methods Mol Biol 141
?Genesis 135
?Embo J 129
?Gene Dev 123
?Dev Biol 108
?J Clin Invest 108
?Cell 104
?Biochem Bioph Res Co 104
?Blood 93
?J Exp Med 93
1 2 3 ...70

1 2 3 ...1294
Top Terms Publications
?Gene Targeting 10,088
?Genes 8,218
?Animals 7,999
?Mice 6,285
?Humans 3,933
?Proteins 3,648
?Mutation


2,441
?Mice, Knockout 2,371
?DNA 2,096
?Phenotype 1,922
?Recombination, Genetic 1,664
?Gene Expression 1,633
?gene express

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